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1.
Article | IMSEAR | ID: sea-226349

ABSTRACT

Uterine prolapse is a type of pelvic organ prolapse where the supporting pelvic structures of uterus weakens and result in descent of uterus from its normal position. Among them, Prasramsini can be most suitably correlated with 1st and 2nd degree uterine prolapse. The management principle of pelvic organ prolapse includes Vathika yoniroga chikitsa along with Sthanika chikitsa. Treatment mainly aims at Vathasamana, Brimhana, Sandhana, Balya and strengthening of pelvic floor musculature. Sthanika chikitsa like Yonilepana, Yonipurana, Pichu dharana, etc can be done in pelvic organ prolapse. In Sthanika chikitsa, medicines are applied intravaginally. Vaginal wall and adjacent tissues are extremely vascular and this facilitates absorption of drugs through vagina. Anatomically backward position of vagina helps in self retaining of drugs for a longer duration. In the present case, Yonilepa as Sthanika chikitsa was tried. A 56 year old lady was presented with complaints of urinary incontinence, low back ache, dyspareunia and feeling of mass per vaginum. On examination, she was diagnosed with 1st degree uterine descend. USG was done to exclude other pelvic pathologies. Pap smear was done which was – ve for intraepithelial lesion or malignancy. Lodhradi lepa was applied for 7 days in 3 consecutive months. During follow up, she was relieved from symptoms like feeling of mass per vaginum, urinary incontinence, low back ache and dyspareunia. From this case report, it is evident that Yoni lepa is effective for the management of uterine prolapse.

2.
Article | IMSEAR | ID: sea-194996

ABSTRACT

Lepa is considered as an important and initial Chikitsa in reference with Vranashotha chikitsa described by Acharya Sushruta and when the Lepa is applied around the outer surface of eyes it is termed as Vidalaka. Vidalaka a type of Kriyakalpa therapy which is mainly indicated in acute inflammatory conditions of eyes such as Daha (burning sensation), Updeha (discharge), Ashru (watering) Shopha (swelling) and Raga (redness). Different formulations are given in classic texts for eye diseases and one among them is Yashtayadi lepa mentioned by Acharya Sharangadhara in Sharangadhara Samhita. It is described as Sarvanetrarujahara Yoga and consists Yastimadhu, Gairika, Saindhav, Daruharidra and Rasanjana as its main ingredients. Yashtyadi lepa was prepared as per the guidelines given for Lepa in API (Ayurvedic Pharmacopoeia of India) and analyzed using various standard physico-chemical parameters given for Lepa such as Loss on drying, Ash value, Water extract value, Alcohol extract value and pH. There is no standard guidelines is given for pharmaceutical analysis for Yastyadi Lepa in API. With this background the present study was undertaken to find pharmacognostical and physicochemical qualities of Lepa as recommended in Ayurvedic Pharmacopoeia of India (API) and to use them as reference for future studies on Yashtyadi Lepa for different ocular diseases.

3.
Article | IMSEAR | ID: sea-194903

ABSTRACT

Children with the clinical features of Chronic Tonsillitis coming under the age group 3-12 years were included in the study. The patients were randomly allocated in to the study group and control group using simple random sampling technique. In the study group the dose of Varabrihatyadi Kashaya was fixed as follows, in the age group 3-6 years: 10ml bd before food, in the age group 6-9 years: 20ml bd before food, in the age group 9-12 years: 30ml bd before food. Sarapunkha lepa was applied around the neck where enlarged lymph nodes were found. Frequency of paste was fixed as two times daily and at each time, it is kept until it becomes dry. At the same time those in the control group were subjected to external application of Sarapunkha lepa only. Both the groups were followed for a period of 1 month after the scheduled course of intervention. Routine blood investigations were also carried out before and after the study. The data were analyzed using the most appropriate statistical tests. Significant changes were obtained in the clinical parameters in the study group used for assessment such as recurrent attacks of sore throat, pain in the throat, pain on swallowing, difficulty in swallowing, halitosis, mouth breathing, hoarseness of voice, chocking spells at night, size of the tonsil, congestion of pillars, oedema of the uvula, deviation of the uvula and lymph node enlargement. There was a significant change in the routine blood investigations also. Moreover the trial drug sustained its potential action even during the follow up period. The effect of control drug was insignificant. The final evaluation proved that combination of Varabhrihathyadi Kashaya and Sarapunkha lepa was effective in reducing the signs and symptoms of Chronic Tonsillitis in children of 3-12 yrs age group.

4.
Article | IMSEAR | ID: sea-194879

ABSTRACT

A 45 year old female patient complaining of pain, Sparsha Asahatwa (tenderness), Shotha (inflammation) crackle sounds of the joints and warmth for 4 years but severe since 5 months and restricted movement of bilateral knee join, was being diagnosed as a case of Janu Sandhigata Vata (Osteoarthritis of knee joint) treatment planned with Hingwashtaka Choorna, Maha Yograj Guggulu, Maha Rasnadi Kadha, Gandharva Haritaki Choorna ausadhi and Bahiparimarjana Chikitsa i.e., Naga Mircha Lepa. There was a significant improvement in the scale of pain, range of movement and standing time along with diminution of inflammation and tenderness after treatment. Patient responded to the Ayurvedic treatment. After the therapy patient felt improvement.

5.
Article | IMSEAR | ID: sea-194833

ABSTRACT

Introduction: Wounds and their management are fundamental to the practice of surgery. In surgery of trauma, wound is frequently a primary pathology. In elective surgery, it is through the wound that access is obtained to deal with the underlying pathology. In both situations surgeon’s task is to minimize the adverse effects of wound, remove or repair damaged structures and harness the process of wound healing to restore function. Objectives: The study is aimed to know the comparative efficacy of Yashada Bhasma Lepa and Jatyadi Ghrita in the management of Dushta Vrana. Method: Clinically diagnosed 30 patients of Dushta Vrana were randomly divided into two groups, each group consisting of 15 Patients. First (A group) is treated by Yashada Bhasma Lepa and second (B group) is treated by Jatyadi Ghrita for 21 days. Result: On the basis of assessment criteria and on the overall result of treatment the patients of Yashada Bhasma Lepa group showed better relief when compared to Jatyadi Ghrita. Interpretation: Yashada Bhasma Lepa having the properties of Tikta, Kashaya, Katu, Rasa predominance thus had action of Kapha Pitta Shamana, Netra Roga, Pandu, Bahumootra Roga, Kasa, Swasa, Rajayakshma, Ratrisweda, Vranasrava Avarodaka,Prameha, Sankochakara.etc. Thus this help for Shodhanaand Ropana. Conclusion: Yashada Bhasma Lepa has provided better relief in maximum signs and symptoms of the patients of Dushta Vrana, in comparison to Jatyadi Ghrita. Its overall effects were also better in comparison to Yashada Bhasma Lepawith Jatyadi Ghrita and dressing reduces the infection.

6.
Article | IMSEAR | ID: sea-194827

ABSTRACT

Skin is one of the five 慓yanindriyas� as described in Ayurvedic texts. It is responsible for 慡parsh Gyan� or touch sensation; therefore it plays a great role in physical and mental health of any individual. It is most affected by fungal infections. According to modern science the fungal infections caused by dermatophytes are called as dermatophytosis. Tinea or Ringworm infection presents with of the circular skin lesions with elevated edges. In Ayurveda, all skin diseases have been discussed under the broad heading of Kushta. The study comprised of a series of 10 patients of Mandal kushta. The patients were selected from OPD and IPD of Kayachikitsa of Sri Krishna Ayurvedic Medical College, Varanasi. In the present study a clinical trial is done with trial drug Panchtiktkta ghrit gugglu and external application of Shirisadi lepa. Panchtiktkta ghrit gugglu is cited from Bhaishajya Ratnavali and Shirisadi lepa is cited from Charak Samhita. Panchtiktkta ghrit gugglu is given in a dose of 2 tablets 3times in a day with the combination of external application of Shirisadi lepa twice in a day for 45 days. Three follow ups with duration of 15 days were done. A remarkable changes were found in various sign and symptoms based on assessment criteria which are Kandu (itching), Sotha (inflammation), Srava (secretions), Vivarnata (discolouration) and Vrana (lesion). It was indeed a proper and suitable approach for this chronic skin disorder as the patients of Mandal Kustha combat a lot for this dreadful disease as it persists for long time and spread rapidly.

7.
J Ayurveda Integr Med ; 2013 Oct-Dec; 4(4): 237-240
Article in English | IMSEAR | ID: sea-173341

ABSTRACT

A 4.5-month-old female baby, presenting with complete paralysis of right upper limb with typical waiter’s tip deformity, diagnosed as Erb’s palsy was brought to Sri Ganapati Sachchidananda Hospital. Patient was treated with an integrated approach of physiotherapy and Ayurvedic treatment with an intention of aiding faster recovery of the patient to lead a near normal life. As per Ayurvedic classics, this condition can be correlated to Ekangavata (Vata effecting any one part of the body), which is Apatarpana in nature (diseases with deprived growth of body tissue). Hence, the choice of treatment is Santarpana Chikitsa (nourishing treatment). Santarpana Bahyopakramas (nourishing external treatment modalities) such as Ashwagandhabalalakshadi Taila (Ayurvedic medicated oil) Abhyanga (oleation therapy) and Shastikashali Anna Lepa (application of processed rice paste) were administered along with electrical stimulation (physiotherapy modality), both galvanic and faradic current in three sessions. Appreciable results were observed in the form of reduction of disparity in length and mid-arm circumference of right upper limb compared to unaffected left upper limb and the muscle power too improved from zero to four, facilitating patient to near normal movement.

8.
Progress in Biochemistry and Biophysics ; (12)2006.
Article in Chinese | WPRIM | ID: wpr-592651

ABSTRACT

During the translation process, aminoacyl tRNA enters the ribosome, decoding the codon on the mRNA and brings the mRNA moving forward towards the 5′ direction of mRNA, until the de-acylated tRNA leaves the ribosome, it moves through the ribosome in one direction. Recently, with the finding and identification of the highly conserved protein LepA, a new kind of tRNA movement inside the ribosome, namely the back-transloation of the tRNAs and mRNA in the direction of mRNA 3′ is discovered. With the in-depth research, the physiological meaning behind the back-translocation for the translational efficiency and fidelity has been studied.

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